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One in vitro fermentation study using human fecal samples compared PHGG with wheat dextrin, a similarly low-viscosity fiber, and found PHGG produced essentially no detectable gas in the first 4 hours, with output rising between 8 and 24 hours 6

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Medullary thyroid carcinoma is the rarest form of thyroid cancer, accounting for 3-4% of all cases, and is the specific type referenced in the warning